I'm sorry for using some technical terms in the last post.
What I meant to say...
1. I still don't understand clearly how the Covaxin works. Even MOA of Covishield is not very clear to me ( possibly due to the lack of understanding of immunolgy beyond very basics)
2. I do understand the MOA of Sputnik and mRNA vaccines just fine.
3. Have no idea about efficacy of the vaccines, however their protective value seems to be much less compared to the claimed values ( I've nothing to substantiate my claim here, but almost everyone in India I know of already received 2 doses of either vaccines and EVERYONE who took the RT PCR test are positive, since the test is not mandatory for doctors in India, no one knows how many of them are actually positive)
4. Measurement of antibodies ( antibody titre) is just a waste of money. It has no diagnostic or prognostic value.
5. Only a small percentage of vaccinated friends in India is having moderate to severe disease, so it may work as BCG vaccine ( which only prevents bad complications of tuberculosis in a certain percentage of recipient, of course a lot of BCG vaccinated people get TB meningitis)
6. All vaccination activities should be stopped when active transmission in a community crosses a certain threhold ( it's an extremely complex calculation and honestly I've forgotten it)
7.Im not a good clinician, all my observations are purely based on statistical correlations and I may be completely wrong.
What I meant to say...
1. I still don't understand clearly how the Covaxin works. Even MOA of Covishield is not very clear to me ( possibly due to the lack of understanding of immunolgy beyond very basics)
2. I do understand the MOA of Sputnik and mRNA vaccines just fine.
3. Have no idea about efficacy of the vaccines, however their protective value seems to be much less compared to the claimed values ( I've nothing to substantiate my claim here, but almost everyone in India I know of already received 2 doses of either vaccines and EVERYONE who took the RT PCR test are positive, since the test is not mandatory for doctors in India, no one knows how many of them are actually positive)
4. Measurement of antibodies ( antibody titre) is just a waste of money. It has no diagnostic or prognostic value.
5. Only a small percentage of vaccinated friends in India is having moderate to severe disease, so it may work as BCG vaccine ( which only prevents bad complications of tuberculosis in a certain percentage of recipient, of course a lot of BCG vaccinated people get TB meningitis)
6. All vaccination activities should be stopped when active transmission in a community crosses a certain threhold ( it's an extremely complex calculation and honestly I've forgotten it)
7.Im not a good clinician, all my observations are purely based on statistical correlations and I may be completely wrong.